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Medical Sciences Journal of Islamic Azad University. 2014; 24 (1): 8-13
in Persian | IMEMR | ID: emr-146939

ABSTRACT

Organic solvents, such as phenol, are widely used in different industries and occupations. The aim of this study was to evaluate the effects of phenol on testicular morphology and morphometry and also some digestive organs and body weight. In this experimental study, 54 male wistar rats were placed in 3 groups, including control and phenol recipient of 100 and 200 mg/kg/bw. Rats received phenol solution or water by gavage every day for 15 days. At the end of study, 3 rats from each group were weighted. After anesthetize of rats, right testes dimensions, weight and histological structure as well as weights of some digestive organs were determined. Phenol at 100 and 200 mg/kg.bw significantly increased the spermatogonia cell count and lumen seminiferus tubule diameter, compared with the control group [p<0.05]. While, 200 mg/kg/bw phenol reduced the epithelial thickness in compared with control group [p<0.05]. Testicular morphometry was not affected by phenol treatments [p>0.05]. Stomach and colon weights in phenol receiving groups were significantly lower than the control group [p<0.05]. The results indicate the effectiveness of phenol on testes morphological structure and gastrointestinal tract organs weight

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